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p53 represses LDHA expression either by directly binding to its promoter or by promoting degradation of the LDHA transcription factor HIF-1 (Zhou et al., 2019

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This was the first report describing an African mouse species with remarkable skin (and other tissue) regenerative capacity, which has led to comparative studies to unravel the mechanisms underpinning its exceptional healing

Given that microglia can exhibit both pro-inflammatory and anti-inflammatory phenotypes depending on the context, future research is likely to explore ways to fine-tune microglial responses to promote neuroprotection and reduce neuroinflammation

Laughlin MH, Simpson T, Sexton WL, Brown OR, Smith JK and Korthuis RJ (1990) Skeletal muscle oxidative capacity, antioxidant enzymes, and exercise training