nrf2 glutathione sod and Oxidative Stress: A General Overview of Mechanisms and Implications in Human Disease The main molecules involved in

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Eugenol also alleviates neuroinflammation by inhibiting IB phosphorylation and blocking p65 nuclear translocation, enhances membrane fluidity, and increases neuronal resilience, thereby mitigating aluminum-induced neurotoxicity, oxidative stress, neuronal loss, and reactive astrocytosis (77)

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Etiology Various factors contribute to the increase in the burden of PD, including the risk factors (diabetes and obesity), genetic mutations, increasing smoking rates, and the growing impact of industrial and pesticide pollution