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Intermittent dietary methionine deprivation facilitates tumoral ferroptosis and synergizes with checkpoint blockade

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Combinatorial therapies with IDO inhibitors and cancer vaccines have also shown progress

FEMS Yeast Res 14:6072

Some key components of the defense signaling cascade that are known to be affected by ROS and NO activity include mitogen-activated protein kinases (MAPKs) and phosphatases ( Figure 2 )