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Figure 3 As mentioned previously, GSH, a tripeptide containing glutamate, cysteine and glycine, (L--glutamyl-L-cysteinyl-glycine) is the master and most potent cellular antioxidant and the most abundant low molecular weight thiol that plays a crucial role in antioxidant defense against cellular ROS/reactive nitrogen species (RNS)-mediated oxidative damage and in the regulation of numerous metabolic pathways essential for maintaining whole body homeostasis

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GPX2, a direct target of p63, inhibits oxidative stress-induced apoptosis in a p53-dependent manner

Methods Mice were exposed to CS for 5 h after which they were rested in filtered air for up to 16 h

doi:10.3389/fphys.2020.00694 12