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Dysfunction of intestinal epithelial cell polarity and function can trigger potent inflammatory responses within the gut, and related to this, mice deficient in Ap1m2, a master regulator of intestinal epithelial cell polarization, demonstrate chronic colitis

The inhibitors (tannic acid, cibacron blue, hematin, ethacrynic acid or the synthesized peptides) were added to the reaction mixture and GST activity was determined