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Sarsasapogenin improves adipose tissue inflammation and ameliorates insulin resistance in high-fat diet-fed C57BL/6 J mice

Researchers have noted that because the two peptides act through overlapping yet distinct pathways, comparative and combination studies help clarify which observed effects are specific to each compound and which are shared between them

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Studies suggest that oxidative stress-induced mechanisms and reduced antioxidant defense, mitochondrial dysfunction, and impaired energy metabolism (NAD + , NADH, ATP, pyruvate, and lactate), are major causes of ASD