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In the current study, KA administration exhibited reduced activation of PI3K/Akt/Nrf2, and increased levels of caspase-3 (total and activated)

Enzymatic activity assays Liver Acetyl CoA carboxylase (ACC), Fatty acid synthase (FAS), glucose-6-phosphate dehydrogenase (G-6-PDH) and malic enzyme (ME) activities were assayed as previously described (Degrave et al

Benzyl alcohol levels in room-temperature-stored vials had fallen to 0.650.75% w/v, below the threshold required to inhibit common contaminants like Staphylococcus epidermidis and Pseudomonas aeruginosa