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However, if extremely high doses are given for a long time, pyridoxine can cause nerve damage leading to numbness or tingling in the hands and feet (peripheral neuropathy)

In vitro studies show a 70% increase in collagen synthesis, greater than that of vitamin C (50%) and retinol (40%).Pickart & Margolina, Int J Mol Sci 2018)

[DOI] [PubMed] [Google Scholar] 189.Soeda S, Aritake K, Urade Y, Sato H, Shoyama Y

Bioresorbable scaffolds with biocatalytic chemotherapy and in situ microenvironment modulation for postoperative tissue repair