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Through these two pathways, which promotes TGF-1/-SMA/collagen I synthesis, driving AVIC-to-myofibroblast differentiation and ECM deposition, linking ER stress to fibrotic phenotypic transformation

16S rRNA gene sequencing and metagenomics are some of the high-throughput sequencing technologies with the ability to identify patient-specific dysbiosis signatures

As a major antioxidant, glutathione interacts with other antioxidants in the body, such as alpha-lipoic acid, vitamin C, and vitamin E, and they mutually enhance each others work

Riboflavin has been shown to improve clinical manifestations in patients with complex II deficiency, potentially preventing disease progression and even reversing symptoms

Reid MA, Dai Z, Locasale JW