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Seek urgent medical attention (via NHS 111 or 999 in an emergency) if you experience severe or persistent abdominal pain, persistent vomiting, signs of dehydration (such as dizziness, reduced urination, or extreme thirst), or symptoms suggestive of low blood sugar (such as shakiness, sweating, or confusion)

Consult Your Doctor Persistent or severe headaches after a B12 shot should be discussed with your healthcare provider: Your doctor can determine if dosage adjustments or different injection methods are needed

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Activation of the mu-opioid receptor reduces pain perception (59)

Also, after 28 days, discard any remaining contents