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Some blends contain higher doses of vitamins and minerals to address nutrient deficiencies

All reagents and experiments conducted in this study are compliant with the institutional biological safety committee (SPROTO202200000081) of the University of Arkansas for Medical Sciences

In contrast to the delayed colonization of the brain, fungal burden increased in the lungs, liver, spleen, and kidneys of mice infected with gsh2 mutants 26 days post-infection, suggesting that gsh2 -infected mice likely succumbed to cryptococcal pneumonia and/or visceral organ damage rather than brain infection (Extended Data Figs

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Ferroptosis inhibitors act by inhibiting iron accumulation and reducing iron overload (e.g., deferoxamine [DFO]) or by inhibiting lipid peroxidation and reducing lipid ROS production (e.g., liproxstatin-1, vitamin E, and ferrostatin1 [Fer-1]) ( DFO has been shown to ameliorate cardiomyocyte injury in an in vitro DCM model of ECT exposed to AGE, reducing the expression of the lipid peroxidation marker malondialdehyde (MDA) and the ferroptosis marker prostaglandin-endoperoxide synthase-2 (PTGS 2 ), improving ECT cardiomyocyte function