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the latter is cleaved by enzyme cysteinyl glycinase to produce free glycine and the cysteine conjugate

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Furthermore, mtDNA activates Z-DNA binding protein 1 (ZBP1), mediating PANoptosis in endothelial cells [21]

Genetic deletion of CD36 or pharmacological inhibition of ferroptosis in CD8+ T cells can restore their cytotoxicity and synergize with anti-PD-1 immunotherapy [41]