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Some observational research has also suggested a slight increase in lung cancer risk linked to long-term, high-dose B6 and B12 supplementation, particularly among men and smokers, although this kind of study cannot prove that the supplements caused the cancers

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This phenomenon is predominantly caused by cobalamin release during hepatic cytolysis and/or decreased cobalamin clearance by the affected liver

Based on the available preclinical research, the peptide appears to have several potential mechanisms of action: It may interact with growth factors like VEGF and EGR-1, promoting angiogenesis and aiding in the recovery of various tissues [3, 8]