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FDA's Official Reasons: Lack of Clinical Trials: The FDA emphasizes the need for extensive, controlled clinical trials, which are currently lacking

Centers for Disease Control and Prevention

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Research demonstrates influence over 31.2% of all human genes affecting pathways from DNA repair and antioxidant defense to stem cell activation and anti-inflammatory response

At the same concentration of 580 M, Cu(OAc) 2 induced a higher upregulation of IL1A than CuCl 2 , while CuCl 2 induced a higher upregulation of IL8, HSPA1A and FOSL1 than Cu(OAc) 2