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These are one of, if not the most rigorously studied class of peptides ever, with many large, placebo-controlled, randomized trials that followed over the past twenty years from the original GLP-1 drugs such as exenatide, approved by the FDA in 2005

The positive outcomes are currently based on a large body of clinical experience and anonymized case reports rather than large trial data

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Influence of microwave hot-air flow rolling dry-blanching on microstructure, water migration and quality of Pleurotus eryngii during hot-air drying