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MAPK Pathway Modulation p38 MAPK pathway suppression significantly inhibits LPS-induced phosphorylation, reducing inflammatory response and cellular stress

These insights lay the foundation for developing novel therapies targeting energy metabolism in neurodegenerative and metabolic brain conditions, with further preclinical studies planned to assess safety and efficacy

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Apr 2021;27(1):8-14

Since vitamin D is a potent stimulator of LL-37 production, this may partially explain the links seen between vitamin D deficiency and increased risk of infections, especially respiratory infections