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The pathogenesis of DN is multifaceted, involving hyperglycemia, dyslipidemia, oxidative stress, mitochondrial dysfunction, and inflammation, which collectively damage peripheral nerves

However, further studies are still needed to optimize its clinical application, including dosage form improvement, combination therapy strategies and long-term safety assessment

Nasser Nasseri, MD Dr

It was intimidating taking the injection since the needle is an entire inch long

These include: Pale or jaundiced skin Extreme tiredness and lack of energy Pins and needles, muscle weakness, cramping, impaired balance Cognitive issues such as anxiety, depression, 'brain fog', psychosis and dementia Red, inflamed tongue Blurred vision What does vitamin B12 do