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Insulin signalling in tanycytes gates hypothalamic insulin uptake and regulation of AgRP neuron activity

Kim et al., 2011), ULK1-associated ATG13 (Jung et al., 2009), and ATG14 (Yuan et al., 2013), which disrupts autophagy induction and autophagosome nucleation and maturation

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Chemotherapy resistance mechanisms were linked to evasion of apoptosis and ferroptosis, increased drug inactivation, decreased drug activation, changes in drug transport, modulations in drug targets, and interactions with components of the TME, such as cancer-associated fibroblasts and tumor-associated macrophages