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A randomized controlled clinical study of 26 patients with myocardial infarction, anxiety, and depression, compared to that of 26 healthy individuals, revealed that ferroptosis is involved in the pathogenesis of cardiovascular and cerebrovascular diseases associated with depression

Although the pathophysiology of ASD is still poorly understood, the interplay between genetic and environmental factors has been suggested to cause the disease 5

Holotransferrin further binds to the membrane protein transferrin receptor (TFRC) to form a complex that is subsequently subjected to endocytosis (26, 31)