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Similarly, the other two control nanoprobes, i.e., (1) ApoE-decorated ApoE-PDHD nanoprobe without GGT responsiveness and (2) GGT-responsive BEAGA-PDHD nanoprobe without ApoE decoration, were prepared using single polymer N 3 -PEG 3.4k -PDHD and BEAGA 2 -PEG 2k -PDHD, respectively

Methods: This study investigates (i) the enzymatic functions of CD38, (ii) the in vitro effects of DARA and ISA on CD38_mediated NAD + degradation in primary MM cells and a representative MM cell line, and (iii) the in vivo dynamics of ADO and its metabolite inosine (INO) in BM and peripheral blood (PB) plasma from MM patients receiving DARA monotherapy

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[CrossRef] [Google Scholar] New horizons in the roles and associations of COX-2 and novel natural inhibitors in cardiovascular diseases